In a new study, researchers at the Biodesign Institute explore a safe and simple treatment for one of the most devastating and perplexing afflictions – Alzheimer’s disease (AD).
Lead authors Ramon Velazquez and Salvatore Oddo, along with their colleagues in the ASU-Banner Neurodegenerative Disease Research Center (NDRC), investigate the effects of choline, an important nutrient that may hold promise in the war against the memory-stealing disorder.
The study focuses on mice bred to display AD-like symptoms. Results demonstrate that when these mice are given high choline in their diet, their offspring show improveChments in spatial memory, compared with those receiving a normal choline regimen in the womb.
Remarkably, the beneficial effects of choline supplementation appear to be transgenerational, not only protecting mice receiving choline supplementation during gestation and lactation, but also the subsequent offspring of these mice.